Neck and collarbone depression pain may be caused by muscle strain, muscle spasm, cervical spondylosis and other reasons. 1. Muscle strain: Neck muscle strain can lead to neck and clavicle depression pain, pressure, swelling, soreness and other discomfort. When the patient carries out a wide range of activities involving the neck or strenuous exercise, such as pull-ups, due to improper exertion or too long a period of exercise, it can cause muscle strain in the neck. 2. Muscle spasm: Long-term head tilted to one side and remain motionless, cold neck during sleep, falling pillow, etc., can occur in the neck muscle spasm, local production of lactic acid and other acidic metabolites, neck and clavicle depression pain, swelling and other symptoms. 3. Cervical spondylosis: degenerative changes of cervical intervertebral discs and intervertebral joints can compress the peripheral nerves, muscles, blood vessels and other tissues, resulting in sensory and motor abnormalities in the innervated area, and the pain can radiate to the upper limbs and cause numbness and other sensory abnormalities. Neck and clavicle depression pain may also be caused by supraclavicular fossa lymph node enlargement, and gastrointestinal tract tumors, etc. It is recommended to consult a doctor for a clear diagnosis and targeted treatment under the guidance of the doctor.