In DIC, blood coagulation disorders are manifested by a hypercoagulable state leading to the formation of microvascular thrombi, followed by a hypocoagulable state leading to hemorrhagic manifestations such as petechiae and ecchymosis of the skin, gastrointestinal and urinary tract bleeding, etc. DIC is the abbreviation for Diffuse Intravascular Coagulation. DIC, which stands for diffuse intravascular coagulation, is a serious syndrome with both thrombotic and hemorrhagic risks that can occur secondary to severe infections, advanced malignancies, extensive burns, and massive surgical trauma. These serious primary diseases can lead to microvascular endothelial damage and activate the body’s coagulation mechanism in many ways, leading to the formation of diffuse microvascular thrombosis; can consume a large number of coagulation factors and platelets, leading to coagulation dysfunction with serious bleeding manifestations, which can be manifested as systemic mucosal bleeding, gastrointestinal bleeding, urinary tract bleeding and intracranial bleeding. When DIC occurs, the condition is critical, and it is necessary to assess the condition according to the patient’s signs, symptoms, and coagulation function test results, and give anticoagulation, supplementation of coagulation factors, fibrinogen, and other targeted treatments, and at the same time, actively treating the primary disease is the most critical treatment. For example, malignant tumors should be treated with chemotherapy (lung cancer – pemetrexed) in time. The use of drugs and treatment should be carried out under the guidance of physicians.