Toothache caused by swelling of the face there is no fastest way to reduce swelling, the causes of which include periapical inflammation, wisdom teeth periapical inflammation, pulpitis, etc., need to be taken for the cause of the medication, surgical treatment, so as to play a role in the reduction of swelling. 1. Periapical inflammation: A toothache that leads to a swollen face may be caused by periapical inflammation. Patients can take oral antibiotics under the guidance of the doctor, such as metronidazole, cefuroxime, or oral pain medication, such as ibuprofen. Patients can take root canal surgery, micro apical surgery, etc.. 2. Wisdom tooth pericoronitis: toothache caused by swelling of the face may also be due to wisdom tooth pericoronitis. Patients can take oral non-steroidal anti-inflammatory drugs, such as aspirin, ibuprofen, etc., or oral antibiotics, such as metronidazole, clindamycin, etc., under the guidance of the doctor. After the inflammation is eliminated, it is recommended to remove the wisdom teeth. 3. Pulpitis: toothache caused by swelling of the face is also considered to be due to pulpitis. Patients can take direct pulp capping, pulp cutting, indirect pulp capping and so on. There are many reasons why a patient may have a swollen face due to a toothache, it is recommended to identify the cause of the disease in a timely manner, and once the diagnosis is confirmed, the patient should actively cooperate with the doctor to take relevant treatment measures.