If you have bitter mouth in the afternoon, you should consider whether there is a dietary factor, such as excessive eating of greasy, fried, spicy and stimulating food or smoking or drinking in the noon or morning, which leads to the aggravation of the original digestive malfunction and thus the symptoms of bitter mouth in the afternoon, especially when there is a combination of liver and biliary diseases, the symptoms of bitter mouth are more likely to appear. The liver and gallbladder mainly secrete bile to promote digestion, and bile can easily reflux if the pylorus of the stomach is relaxed, thus corroding the stomach wall and causing damage to the gastric mucosa, and may further cause the symptoms of bitter mouth, which should be treated with bile and drugs that promote gastrointestinal motility.