High urine microalbumin may be caused by physiological factors, pathological factors, pathological factors such as diabetic nephropathy, hypertension kidney damage, etc. It is recommended that the patient go to the hospital for a detailed examination to clarify the cause of the disease and then treat the symptoms. 1. Physiological factors: If strenuous exercise, high protein diet, fever, mental stress, etc., there can be a transient increase in urinary microalbumin. Generally, after removing the triggers, it can be normalized. 2. Pathologic factors: (1) diabetic nephropathy: if the patient suffers from diabetes mellitus, and at the same time the urine microalbumin is high, it may suggest that there is the possibility of diabetic nephropathy, and with the development of the disease, the patient may have a large amount of proteinuria, generalized edema. (2) Hypertensive renal damage: patients due to hypertension may lead to kidney metabolism related to nephropathy, resulting in glomerular filtration membrane damage, so there will also be, urine microalbumin is elevated. In addition, it may also be nephritis or urinary tract infections and other diseases caused by urinary microalbumin elevated causes, it is recommended that patients go to the hospital in a timely manner to improve the relevant examination, to clarify the cause of the disease, and comply with the doctor’s instructions for treatment.