Bone pain all over the body, consider osteoporosis, rheumatism, fever and so on. 1. Osteoporosis: Osteoporosis is a metabolic bone disease, and the reduction of bone formation and bone resorption increase, commonly found in middle-aged and elderly patients, osteoporosis will cause symptoms of fatigue, but also the whole body of the bone, the pain is generally diffuse, there is no fixed point of pain. 2. Rheumatism: Rheumatism is a chronic disease that involves the bones and joints and the surrounding soft tissues, the main symptom is muscle and joint pain, usually wandering pain, and after getting up in the morning the pain is heavier, and the symptoms will disappear after the activity. 3. Fever: If the fever is more serious, the muscles will produce heat through contraction, and the excessive contraction of the muscles will also cause generalized pain, which some people may mistake for bone pain. Generalized bone pain may also be other causes, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment or standardized treatment.