Patients with hypothyroidism who are minimally asymptomatic are mainly treated with medication and regular review, and it is recommended to follow the doctor’s instructions for treatment. Hypothyroidism is an endocrine disease caused by thyroid hormone insufficiency or thyroid hormone resistance resulting in decreased body metabolism. In this case, levothyroxine sodium tablets should be used under the guidance of a doctor to maintain the thyroid hormone within a reasonable range. In addition, subclinical hypothyroidism can also have elevated thyroid stimulating hormone (TSH) but normal thyroid hormone levels, and generally have no obvious clinical manifestations. Thyroid hormone therapy should be given to patients with symptoms of hypothyroidism, positive TPOAb, dyslipidemia, or atherosclerotic disease. Patients with hypothyroidism should actively cooperate with their doctors.