Small red spots on the chest and back that disappear when pressed may be caused by spider nevi. Spider nevus can be caused by high estrogen levels or cirrhosis of the liver. Spider moles can be caused by physiological factors, such as high estrogen levels, which can lead to small red dots on the chest and back that disappear when pressed. It can also be caused by pathological factors, such as viral hepatitis, cirrhosis and other diseases. Spider nevi usually appear on the face, neck, chest, back and other locations, after the pressure is lifted, the small red dots will usually reappear, and there will be varying degrees of capillary dilation around the nevus, in a radial shape. If the spider nevus is induced by high estrogen level during puberty or pregnancy, no treatment is needed. If the spider nevus is induced by cirrhosis of the liver, it can be treated with oral medication such as hepatocyte growth promoter and reduced glutathione to promote liver repair. If the small red spots on the chest and back disappear after pressing, it is recommended to go to the hospital for relevant examinations to clarify the cause of the disease and follow the doctor’s instructions for treatment.