The specific reasons for feeling a significant blockage in the stomach are as follows: 1. It should be considered to be caused by digestive system diseases, such as gastroesophageal reflux disease, chronic gastritis, and digestive tract tumors; 2. Cardiovascular diseases or occupational diseases may lead to significant blockage and swelling in the stomach; 3. It may be related to systemic diseases, gastrointestinal dysfunction, incorrect diet, or environmental stimuli, in In this case, you will not only feel a significant swelling in the stomach, but also accompanied by hiccups, acid reflux, nausea, vomiting and significant pain in the sternum. If recurrent attacks occur, it is also recommended not to ignore them and to undergo a gastroscopy. If there is also significant chest tightness, it should be ruled out if there is a heart problem, which can only bring better results if it is really under control.