Secondary radiofrequency ablation has the potential to be curative. Radiofrequency ablation refers to the use of high-frequency electric current in the diseased tissue to produce thermal effects, so that the diseased tissue destruction, in order to achieve the purpose of treatment. In clinical practice, the second radiofrequency ablation surgery is possible to cure, but the success rate of the surgery is not 100%, which is mainly affected by the degree of the patient’s condition and the doctor’s technical experience and so on. Radiofrequency ablation is a widely used treatment in recent years in the medical field, which is often applied to cardiac arrhythmia, and can also be used in the treatment of herniated discs, high blood pressure, tumors (especially liver cancer and limited stage lung cancer) and other diseases. Contraindications to radiofrequency ablation include systemic infections, thrombus in the heart cavity, and patients with serious bleeding tendency. Before secondary radiofrequency ablation, patients should be examined and excluded from the contraindications after comprehensive evaluation by doctors, and patients should keep a good mindset and actively cooperate with doctors.