The main causes of multi-organ failure are severe infections, trauma, large burns and other diseases. The current main treatment is divided into two steps, the main measures for the treatment of multi-organ failure and specific treatments for each damaged organ are as follows: 1. The specific treatment methods for each damaged organ: the treatment methods vary for different organs, the respiratory system to maintain airway patency, oxygenation, ventilator support therapy, prevention and control of pulmonary edema; the circulatory system to maintain normal circulatory function is the basis for maintaining positive tissue blood perfusion and restoring the function of each organ, maintaining effective Circulating blood volume, application of vasoactive drugs, other circulatory function support method can maintain normal circulatory function; liver to maintain blood volume, ensure the liver blood supply based on strengthening support therapy, supply vitamins, supplement calories, supplement fresh plasma albumin or branched-chain amino acids, conducive to the protection of the liver and promote the synthesis of protein by liver cells; use diuretic dialysis therapy, avoid the application of drugs that are damaging to the kidney For bleeding caused by a significant drop in platelets or blood factors, and transfusion of concentrated platelets or fresh frozen plasma, fibrinogen should be supplemented promptly when fibrinogen drops <1g/L.