Patient: Stomach pain for about two years, often throwing up when eating. Gastroscopy was done several times during the period of laboratory tests and treatment, and the ulcer surface was not reduced. From April 20 of this year to the present, he has been treated at Shaanxi College of Traditional Chinese Medicine and the Hospital of the Fourth Military Medical University with medications such as pendolazol intravenously and imported Loxacol. No results. The doctor is now recommending surgery. Please ask Dr. Sun if the surgery should be performed and what will be the sequelae. Sun Weihao, Department of Gastroenterology, Jiangsu Provincial People’s Hospital: Your problem is a bit complicated. The pyloric ulcer with pyloric obstruction causes you to vomit frequently after eating. If it is a benign ulcer, it should be effective after applying pandolazol and omeprazole (Loxac) treatment. And for two years the ulcer surface did not decrease and the symptoms did not improve. So, it makes sense for the doctor to recommend surgical treatment. However, I am worried if it is not a normal ulcer, your age and gastroscopy results do not look malignant (cancer), but Crohn’s disease should be ruled out. If it is this disease surgery should be done carefully and cautiously, it is still recommended that you get a good look from a gastroenterologist at your local hospital.