Fluoxetine is a selective 5-hydroxytryptamine reuptake inhibitor, mainly used for the treatment of depression, bulimia nervosa, and obsessive-compulsive disorder. Adverse effects include headache, nervousness, abnormal sleep, heavy head, sweating, general or local allergy, nausea, vomiting, diarrhea, and also tachycardia, fatigue, visual abnormalities, dyspnea, etc. It is generally not used as a drug for insomnia. Patients with insomnia should try to find the cause and never use drugs indiscriminately. Patients with physiological insomnia are advised not to eat too much at night, not to drink more water before going to bed, not to drink green tea after 4:00 pm, to develop good sleep habits and not to stay up late. Before going to bed, you can drink a small amount of milk, use warm water to soak your feet and massage the soles of your feet to improve sleep.