High fever has been recurring, caused by many factors, commonly found in infections, autoimmune diseases, tumors, etc., need to clarify the cause of the disease for symptomatic treatment. 1. Infections: especially respiratory infections, gastrointestinal infections and urinary tract infections, patients can have recurrent fever, need to carry out anti-infective treatment, commonly used drugs such as azithromycin, erythromycin, amoxicillin and so on. 2. Autoimmune diseases: such as systemic lupus erythematosus, rheumatoid arthritis, dry syndrome, connective tissue disease, etc., patients will have different degrees of fever, glucocorticoids, immunosuppressants, biologics and other treatment. 3. Tumor: Tumor cells can secrete a large number of tumor necrosis factor, interferon, interleukin, etc., which act on the thermoregulatory center of hypothalamus and cause fever, and need to be considered for surgical resection. There may be other reasons for the recurrent high fever, and it is necessary to go to the hospital in time to do relevant examinations, including blood routine, urine routine, C-reactive protein, chest radiographs, rheumatoid factor and tumor-related antigens, etc., so as to make a clear diagnosis, and then symptomatic treatment. If you need to use medication, it is recommended that you do so under the guidance of a physician to avoid blindly using medication on your own and delaying your condition.