Alcohol can be consumed 7 days after a penicillin shot. After intravenous injection of penicillin, it needs to be metabolized before drinking alcohol, which takes about 7 days. Alcohol will affect the body’s absorption and utilization of penicillin to a certain extent, reducing the efficacy of the drug, and the ethanol in alcohol will inhibit the activity of liver drug enzymes, which is not conducive to the metabolism of the drug, leading to an increase in the concentration of the drug in the blood, which is prone to cause adverse reactions in the human body. Penicillin and alcohol have a certain gastrointestinal stimulation, if drinking alcohol during this period will easily make the patient vomit, nausea and other gastrointestinal discomfort, and will increase the burden on the kidneys, and in serious cases, it will damage the function of the liver, causing transaminase elevation. Penicillin is allergic, it is recommended that patients applying the drug to observe whether there is panic, dizziness, dyspnea and other allergic reactions, adverse reactions are serious need to consult a doctor in a timely manner.