Red blood cell deformities may cause dizziness, but headaches are less common. Normal red blood cells in the human bloodstream are shaped like discs with slightly concave sides, and this shape of red blood cells ensures that they are less likely to be destroyed in the blood circulation. When deformation of red blood cells occurs, such as oval or spherical red blood cells, it can be seen in diseases such as hereditary spherocytosis and hereditary elliptocytosis. Deformed red blood cells can be destroyed in large quantities in the spleen and hemolytic anemia occurs, which leads to ischemia and hypoxia of brain tissue, resulting in dizziness, but often without obvious headache symptoms. If the patient is accompanied by headache symptoms, it is necessary to further improve the cranial CT, MRI and other related examinations to clarify the cause of the disease and provide targeted treatment.