Multiple grinding glass shadows in the lower lobe of the left lung is an imaging description that suggests the presence of a lesion in the lower lobe of the left lung, which may be inflammation, edema, fibrosis, or tumor. Pulmonary ground glass shadows are mildly elevated cloudy, pale shadows of parenchyma on high-resolution CT images and are often a sign of early lung disease. If the patient has fever, elevated inflammatory indicators, etc., consider the possibility of infection, further anti-infection and then review the CT, if the ground glass shadow becomes smaller or disappears, then it is inflammatory. Interstitial fibrosis can cause multiple ground-glass shadows, which mainly manifests as active dyspnea with gradual aggravation, mostly accompanied by dry cough, and requires glucocorticoid and immunosuppressant treatment. Diffuse alveolar carcinoma or metastatic carcinoma of other tumors may present multiple ground glass nodules in the lungs, which need to undergo lung tissue biopsy to clarify the pathology of the tumor and further anti-tumor treatment, and the prognosis is poor, and the advanced stage may be complicated with multiple organ failure. In case of multiple ground glass shadows in the lower lobe of the left lung, the next examination should be carried out in time to clarify the specific cause of the disease, and the relevant treatment should be taken according to the doctor’s instruction to avoid delaying the condition.