A Down’s child is a child with pediatric Down’s syndrome. Pediatric Down syndrome, also known as trisomy 21, is caused by an extra chromosome 21 in the child’s body, and is related to the mother’s advanced age, genetic predisposition, teratogenic substances and other factors. People with this disease are often characterized by intellectual backwardness, special facial features, growth retardation, and often accompanied by congenital heart disease, gastrointestinal malformations and other malformations. At present, there is no effective treatment for pediatric Down syndrome, if long-term patient education and rehabilitation training, most of the children can master certain life skills, basically can realize the life of self-care, so the children should follow the doctor’s advice and active treatment. In addition, screening programs for Down’s syndrome during pregnancy include Down’s syndrome screening and NIPT; intrauterine diagnostic methods include chorionic villus aspiration, amniocentesis, and umbilical cord blood sampling, which should be performed in accordance with medical advice.