Pineal gland calcification is the manifestation of calcification of the pineal tissue in the skull, which belongs to the intracranial glandular tissue and gradually increases in size with growth and development. After the age of 10-14 years, as the glandular cells gradually decrease, the connective tissue and neuroglial proliferation occurs and a calcium clot, the so-called brain sand, appears. Composed of carbonate forms of calcium and magnesium and phosphate forms, this phenomenon is called pineal gland calcification, which is a normal structural variation and does not require treatment. Attention is needed when the following conditions are present on MRI, including pineal calcification greater than 12 mm, pineal calcification significantly deviating from the midline, and pineal calcification occurring in children younger than 10 years of age, requiring further medical attention.