In the past, diabetic lower extremity lesions (mainly including occlusive atherosclerosis and diabetic foot) have been a problem for diabetic doctors because of the difficult to restore blood flow to the lower extremity and the persistent foot ulceration. Conservative treatment is ineffective and disabling, and a significant proportion of patients cannot escape from the fate of resting pain, limb gangrene and even eventual amputation. Nowadays, diabetologists have greatly reversed this fate by treating diabetic lower limb lesions with multidisciplinary and multiple techniques. 1. Targeted understanding of blood supply: Vascular imaging makes accurate diagnosis of lower extremity vaso-occlusive disease, preoperative treatment planning and postoperative follow-up a reality. Initial screening can be performed with color Doppler ultrasound, which is non-invasive, easy to perform and inexpensive. Lower extremity angiography (DSA) can be used to visualize the vascular lumen. The most promising vascular imaging is multilayer spiral CT angiography (CTA), which is fast, safe, and noninvasive, and can adequately show the presence, degree, and extent of lower extremity vascular stenosis or occlusion, as well as the presence of collateral circulation and plaque. With angiography it is possible to follow the map and reconstruct the blood flow. 2. Each of the hemodynamic reconstructions: hemodynamic reconstructions are the key to reducing pain, saving the limb or minimizing the amputation plane. Choose the appropriate treatment according to the characteristics of the vascular lesion. Percutaneous transluminal balloon angioplasty (PTA) and stentoplasty (PTAS) are the most commonly used because of their minimally invasive nature and rapid hemodynamic recovery, which has saved many affected limbs from amputation. For small blood vessel occlusion below the knee, stem cell transplantation can be performed. This has resulted in improved blood supply in 87% of ischemic limbs. Recently, Deep balloon dilation has emerged, and its limb saving rate is over 80%. Endoluminal plaque resection is an emerging endoluminal treatment where stem cell (single nucleated cell) transplantation can induce neovascularization of the ischemic limb, which in turn improves the limb blood supply. With single nucleated cell transplantation, the ankle-brachial index increases and imaging shows significant collateral angiogenesis, decreasing the amputation rate and contributing to healing of most ulcers. A combination of stem cell lower limb arterial intraluminal/lower limb local intramuscular/lower limb arterial intraluminal and lower limb local intramuscular injection therapy was implemented. 3.Ultrasound debridement is bloodless: for foot ulcers that have occurred, especially deep and large wounds with serious infection and decay deep into the muscle layer and ligament that have not healed for a long time, the unique technology of ultrasound debridement machine is applied to destroy and remove bacteria from superficial and deep tissues, and the bacterial removal rate is up to 95% or more, and it is painless to remove fibrin and necrotic tissue deposited in chronic infected wounds and wounds to promote granulation tissue Growth, tissue repair fast. 4, efficient dressing change scratch: silver-containing antibacterial sheet gel dressing is a synthetic polyendothelial acid polymer containing silver chloride, is an amorphous wound dressing for moist wound care to maintain the best moisture environment for the wound, can absorb minor secretion or provide moisture for the wound. At the same time, this dressing is an effective barrier against germs invading the wound. Its antimicrobial barrier effect can prevent and reduce wound infection. It can induce endothelial cell migration, promote capillary proliferation, form capillary-rich granulation tissue, and promote wound healing.