Hepatitis B Virus Markers

  1. Hepatitis virus markers: About 80% of chronic liver diseases in China originate from hepatitis B or C virus. The presence of hepatitis virus infection can be easily detected by blood tests (hepatitis markers). It is also possible to understand the status of the virus infection.  2, hepatitis B virus markers: (1) hepatitis B surface antigen: is the shell component of the hepatitis B virus, the blood test is positive that indicates infection with the hepatitis B virus.  (2) Hepatitis B surface antibody: is the antibody produced by its own body in response to the surface antigen, if the blood test is positive, it means that the immunity to the hepatitis B virus has been generated, the surface antigen is positive that the patient infected with the hepatitis B virus is negative for the surface antibody.  (3) Hepatitis B core antigen: It is the core part of the hepatitis B virus. It is not easily detected in blood tests and is usually detected in liver biopsies.  (4) Hepatitis B core antibody: It is an antibody produced by the body in response to the core antigen. Therefore, it indicates the possibility that the body is currently infected with the hepatitis B virus or has been infected in the past and has left traces.  (5) Hepatitis B e antigen: Hepatitis B e antigen is a substance produced during the proliferation of the hepatitis B virus. Therefore, only if the surface antigen is positive, that is, only if the present state is infected with hepatitis B virus, the e antigen may be positive. A positive e antigen indicates a high concentration of virus in the blood, active virus proliferation, and high infectivity. When antiviral treatment for hepatitis B is administered, the disappearance of the e antigen indicates a response to treatment.  (6) Hepatitis B e antibody: This is an antibody produced by the body against the e antigen. the disappearance of the e antigen is usually accompanied by the production of e antibody. When the e antigen disappears and the e antibody is positive, the proliferation of hepatitis B virus is at a low level.  (7) Hepatitis B virus DNA: When HBV-DNA is positive, it means that there is now hepatitis B virus infection, and the higher its concentration the more active its proliferation. Clinically, it is usually combined with e antigen to monitor the response to antiviral therapy.