Common causes of chronic renal failure include primary renal diseases, secondary renal diseases such as hypertensive renal small arteriosclerosis and diabetic nephropathy. 1. Primary renal diseases: primary glomerulonephritis, tubulointerstitial disease, chronic pyelonephritis, etc. Continuous inflammation may destroy the structure and function of the kidney, leading to deterioration of renal function. Primary glomerulonephritis is the most common cause of chronic renal failure in our country, and it needs to be treated with drugs such as cyclosporine, prednisone, etc under the guidance of the doctor after diagnosis. 2. Secondary causes: hypertension, diabetes, systemic lupus erythematosus and other diseases, in poor control may cause renal function damage, resulting in chronic renal failure. It is necessary to actively control blood glucose and blood pressure, treat the primary disease and monitor the renal function. Chronic renal failure may also have other causes, it is recommended that patients go to regular hospitals in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.