For the treatment of peripheral nerve problems, nerve release surgery is advocated in many places. Our Dr. Minqin Yuan discussed this issue in depth when he went to Sichuan this year to talk with front-line doctors in China. So, does diabetic peripheral neuropathy have good results with relaxation surgery? First, let’s understand the mechanism of neuropathy. The peripheral nerve begins in the spinal cord and innervates the fingers and toes, and there are multiple anatomical stenoses along this pathway. Each person has these physiological stenoses, which cause the nerve to be more susceptible to compression within them. When they are under pressure, a release surgery can relieve the pressure, which can relieve the symptoms of neuropathy. Second, peripheral nerves are mostly swollen in diabetic patients. Under normal circumstances, blood sugar enters the nerve to remind heat and convert it into fructose. High blood sugar causes a large amount of fructose to accumulate in the peripheral nerves of diabetic patients. Fructose, in turn, combines easily with water, so water is drawn into the nerve causing it to swell, which increases the pressure on the nerve. Third, damaged nerves in people with diabetes have difficulty repairing themselves. Nerves are filled with a variety of substances that allow important chemical messages to pass through the nerve before the central nerve can understand what is going on at the distal end. Unfortunately nerve cells are very difficult to continue to regenerate, so other methods can only be used to relieve symptoms, which is one of the considerations that has led to the preference for release surgery to decompress. Can decompression surgery done on nerve compression be used for peripheral neuropathy due to diabetes? According to the principle, diabetes causes swelling and decompression is certainly effective in relieving the compression and improving the blood supply to the nerve by cutting through ligaments or fibrous tissue to loosen the compressed area on the nerve pathway. However, surgery does alter the natural course of diabetic neuropathy, as it is the local compression of the nerve that causes the symptoms. However. Nerve decompression surgery does not resolve abnormal metabolic neuropathy and does not reverse the diseased nerve. In other words, if the surgery is done in the early stage, the result is very good, but when the lesion is already severe, it is more risky to do it instead. This is because surgery is not good enough to relieve the symptoms of diabetic peripheral neuropathy, and the wounds of diabetic patients are inherently difficult to heal, and decompression surgery requires cutting healthy tissue in the legs, arms, feet, etc. Who can guarantee that such wounds will not become infected? Who can guarantee that such wounds will not become infected? Especially for patients who have already developed diabetic foot ulcers and infections, they should not do decompression surgery to avoid adding new wounds before the old ones heal.