Anemia does not usually lead to high D-dimer, and high D-dimer is seen in diseases such as DIC, leukemia, and pulmonary embolism.
Anemia is defined as a decrease in the volume of red blood cells in the peripheral blood of the body below the lower limit of the normal range, including macrocytic anemia, normocytic anemia, and microcytic hypochromic anemia.
Laboratory findings vary between the different types of anemia. Iron deficiency anemia is mainly characterized by a decrease in extra- and intramedullary iron, and megaloblastic anemia is mainly due to deficiencies of vitamin B12 and folic acid, but the anemia does not usually result in a high D-dimer.
D-dimer is used to rule out deep vein thrombosis and pulmonary embolism, and can be elevated in discrete intravascular coagulation, certain leukemias, and pulmonary thromboembolism.
Prompt medical attention is recommended in case of discomfort.