The mechanism of muscarinic symptoms is the excitation and then inhibition of cholinergic nerve impulses caused by the accumulation of acetylcholine, which is reflected in the clinical symptoms associated with increased glandular secretion and smooth muscle contraction. For example, patients may experience excessive sweating, lacrimation, runny nose, salivation, diarrhea, frequent urination, nausea, vomiting, abdominal pain, urinary and fecal incontinence, slowed heartbeat, narrow pupils, blurred vision, decreased blood pressure, respiratory distress, and pulmonary rales, which are usually caused by organophosphorus pesticide poisoning. In the treatment, cholinesterase resuscitating drugs, chlordimeform, chlorophosphamide, double compound phosphorus application is more common. However, since these drugs cannot restore the cholinesterase effect of aging, clinical treatment is often combined with atropine, which has the effect of blocking acetylcholine to parasympathetic and muscarinic receptors in the central nervous system. During treatment, atropine should be adjusted depending on the patient’s condition until the patient shows signs of atropinization.