Pain on pressure under the ribs in the right abdomen may be due to several reasons. First, there may be a muscle-related injury in this area, as seen in patients who have suffered direct violent blows or excessive activity, resulting in muscle-related injury in this area, and there will be significant pressure pain in this area. Secondly, it may be caused by cholecystitis, and the site of such pain is located at the intersection of the rectus abdominis muscle with the rib arch. The pain is very pronounced when pressed and may lead to restriction of breathing. Third, it may be caused by appendicitis. The site of this pain is located at the intersection of the umbilicus and the external 1/3 of the anterior superior iliac spine. Fourth, it may be caused by gynecological diseases in women, such as pelvic inflammatory disease, adnexitis or ectopic pregnancy. Fifth, it may also be caused by lesions related to the urinary system, such as the presence of nephritis, ureteral stones and a series of other diseases.