AIDS patients may not have fever if there is no obvious chance of infection, but during the onset of the disease, some patients may have prolonged unexplained fever, which is irregular and may last for more than a month, with body temperature above 38 degrees. In addition to prolonged fever, there will be chronic diarrhea, weight loss, night sweats, memory loss and personality changes. In addition to these clinical symptoms, various opportunistic infections, such as respiratory, central nervous system, and digestive system, are most common during the onset of AIDS. Some patients develop with malignant tumors, such as malignant lymphoma, Kaposi’s sarcoma, etc. For AIDS patients, timely antiviral treatment is definitely needed, and antiviral treatment can improve prognosis and survival time.