Sleeping at night with numbness in the legs and hands can be considered as a result of pressure, seen in prolonged pressure, resulting in poor local blood circulation. If the leg numbness and hand numbness is partial, it can also be seen clinically in cerebrovascular diseases, such as cerebral infarction and transient ischemic attack, which are prone to ischemic cerebrovascular diseases due to slowed blood flow at night during sleep, especially in patients with atherosclerosis. Some patients with U-shaped hypertension and high blood pressure at night can also develop cerebrovascular rupture, leading to cerebral hemorrhage causing leg and hand numbness, which can be diagnosed after a CT or MRI examination of the head. Numbness in the legs and hands at night can also be seen in peripheral neuropathy, mostly caused by alcohol, due to heavy alcohol consumption, or malnutrition and diabetic peripheral neuropathy, the patient can have numbness in the legs and hands, and will not be relieved after sleep. Numbness of legs and hands in sleep can also be seen in cervical and lumbar spine diseases, which can be caused by cervical disc herniation, lumbar disc herniation and lumbar spinal stenosis, etc. Patients are mostly accompanied by pain in the neck and shoulders.