The treatment of blisters on the forefoot is mainly divided into general treatment, blister fluid extraction and drug treatment. 1. General treatment: pay attention to rest and braking, avoid movement, avoid further stimulation, friction and injury of local trauma. Keep the local skin dry and clean to avoid secondary bacterial infection. 2. Herpes extraction: for large blisters can be sterilized with povidone-iodine, then use a sterile syringe to extract the blisters, and then appropriate pressure bandage to promote healing. The specific operation needs to go to the hospital to be carried out by professional doctors. 3. medication: erythromycin ointment or mupirocin ointment can be applied to the wound after extraction of the blisters to prevent infection. Specific medication should be under the guidance of a doctor, do not take medication without authorization. If the patient’s symptoms are obvious and persistent, it is recommended to consult a doctor in time to avoid delays in the condition