Whether thickening of the wall of the gastric sinus is serious or not depends on the cause of the condition. Common causes include inflammatory diseases, ulcerative diseases, and neoplastic diseases. The thickening of the sinus wall caused by inflammatory diseases is not serious, while the thickening caused by ulcerative diseases and tumor diseases is more serious. 1. Inflammatory diseases: for example, gastritis, gastritis, etc., mainly the existence of inflammation in the gastric sinus, there may be the phenomenon of Helicobacter pylori infection, which is relatively not very serious, and through the standardized treatment, it will get a better prognosis. For example, Helicobacter pylori infection, can be under the guidance of the doctor, the application of drug therapy, commonly used are clarithromycin, amoxicillin, omeprazole and colloidal bismuth pectin. 2. Ulcerative diseases: if the patient is caused by gastric sinus ulcer, which is relatively more serious, if not treated in time, it is easy to cause bleeding, perforation and other phenomena, but also easy to lead to pyloric obstruction, and may even induce cancer. 3. Tumor disease: the presence of tumors and other occupying diseases in the gastric sinus area, such as gastric cancer, gastric lymphoma and so on, can also cause such a phenomenon, which is more serious, because it may be malignant, and need to do further examination, and if necessary, can be biopsied, to help analyze the nature of the tumor. Gastric sinus wall thickening suggests that patients actively undergo relevant examinations to clarify the cause of the disease and then actively carry out effective treatment.