Creatinine 169μmol/L often means that the kidney function is in the decompensated stage of renal insufficiency, and the glomerular filtration rate may be around 50ml/min. As for whether you can drink more water, it depends on the patient’s specific situation. If the patient does not have edema, urine protein is not much, you can drink more water, but not too much, drinking too much water will also increase the burden on the kidneys. If the patient already has edema or edema has been more obvious, and the kidney function is not good, then the amount of water needs to be controlled. If the patient has poor kidney function, the kidney’s ability to regulate the water balance is relatively poor, so it is easier to drink water in, but the kidney function is relatively poor to discharge, and it may become more and more swollen. Severe edema may lead to an increased burden on the heart, resulting in impaired heart and lung function, which may be life-threatening in severe cases. Therefore, the amount of water to drink depends not only on the creatinine level, but also on whether the patient has edema. As long as there is no edema, you can drink water appropriately, and if there is edema, you should limit the amount of water you drink.