There is no query on the latest advances in conservative treatment of gastric perforation. However, conservative treatment is generally not recommended. Conservative treatment of gastric perforation has the potential to cause severe abdominal infection due to delay. Therefore, in clinical practice, conservative treatment is generally not recommended in favor of aggressive surgical treatment to repair the perforation and clean up the inflammatory lesion. During the above treatment, gastrointestinal decompression, the use of acid suppressants, anti-infection and other methods of relief to promote recovery can be chosen according to different situations. After gastrointestinal decompression, digestive fluids can be drained out of the stomach in large quantities in a short time, effectively blocking the leakage of digestive fluids into the abdominal cavity, reducing peritoneal inflammation, and effectively relieving patients’ abdominal pain symptoms. The use of acid inhibitors including famotidine, ranitidine, omeprazole, rabeprazole, etc. can play the role of inhibiting gastric acid secretion and protecting gastric mucosa. Antibiotic treatment should also be given according to the results of pathogenic bacteria testing to control infection and eliminate the symptoms of abdominal infection. Gastric perforation is an emergency, once found, must be promptly to the hospital for treatment, the doctor will choose the appropriate treatment according to the patient’s condition, so as not to delay the condition.