The eyelids may not open due to the following conditions: first, congenital factors that cause hypoplasia of the levator muscle, causing congenital ptosis, and for those with more severe symptoms or monocular ptosis, timely surgical correction is required to avoid the formation of amblyopia; second, myasthenia gravis, which manifests itself as fluctuating morning lightness and evening heaviness, as well as aggravation after exertion and reduction after rest; third, arteriovenous nerve palsy, such as compression by cerebral aneurysm The third is arterial nerve palsy, such as cerebral aneurysm compression, diabetic peripheral neuropathy, cerebrovascular disease, multiple sclerosis, and occupancy, resulting in ptosis; the fourth is sympathetic nerve palsy, which results in Horner’s syndrome and a smaller eye fissure; the fifth is orbital trauma; the sixth is upper eyelid lift weakness in the elderly, which can be corrected with blepharoplasty; and the seventh is blepharospasm. The six conditions described above are caused by upper eyelid weakness and paralysis, while blepharospasm is a spastic disease of the orbicularis oculi muscle that causes the eyelids to close involuntarily, often with bilateral lesions, and in severe cases the eyelid spasm is so pronounced that it makes it difficult to open the eyes and affects the ability to see the surroundings, causing functional blindness.