The corners of the mouth outward radiating wrinkles is due to keratitis and other diseases caused by keratitis, keratitis triggering factor is the cold dry climate, will make the lips, the corners of the mouth around the skin mucous membranes dry and cracked, around the germs to take advantage of the situation caused by infection, caused by keratitis; lips dry and cracked, people often habitually licked with the tongue, which is more prone to make the corners of the mouth dry and cracked; if the intake of vitamins from dietary reduction, resulting in a lack of the B vitamins, can also lead to the occurrence of vitamin B deficiency of the corners of the mouth, the mouth is not a good idea. Vitamin B deficiency can also lead to the occurrence of keratitis. What are the checkups for outward radiating wrinkles at the corners of the mouth? The following is a description of the radiographic wrinkles of the corners of the mouth outward examination items: initially dry lips, corners of the mouth erythema, edema, oozing, crusting. Into the chronic when the local mucous membrane skin moist, cracked, rough flaking occurred to the corners of the mouth outward radioactive wrinkles. If caused by malnutrition, anemia, riboflavin deficiency can be accompanied by oral, tongue and pubic mucosal damage, such as glossy tongue, scrotal skin redness and corresponding systemic symptoms. Mostly bilateral symmetry, can also be unilateral onset. Self-conscious burning sensation. In malnourished children, pustules may appear at the corners of the mouth and its surroundings, mostly related to Pseudomonas aeruginosa infection. Dry lips, the corners of the mouth can occur maceration, wetness, vesicles, cracking, self-conscious burning sensation. Diagnosis can be made on the basis of clinical manifestations.