There is no single oral hypoglycemic agent that is absolutely optimal for lowering blood glucose, and it is recommended that you consult with your doctor to choose the right medication for your condition. Oral hypoglycemic drugs mainly include biguanides, α-glucosidase inhibitors, sulfonylureas, glinides, thiazolidinediones, DPP-4 inhibitors, SGLT-2 inhibitors, and new GLP-1 agonists. Different hypoglycemic drugs have different mechanisms and are applicable to different groups of people, so it is recommended to follow the doctor’s instructions. It is recommended that diabetic patients apply hypoglycemic drugs to lower blood glucose on the basis of strict diabetic dietary control, monitor blood glucose regularly, and adjust the type and dosage of hypoglycemic drugs by specialized physicians.