It is a sexually transmitted disease caused mainly by the simple scar virus type 2 (HSV-2). The infection is prone to recurrence and can cause miscarriage and neonatal death in women, and may also be associated with the development of cervical cancer, which should be taken seriously.
Pathogen
Herpes simplex virus is a DNA virus, humans are its natural host, there are 2 types of HPV, 90% of the transmission route through sexual intercourse HSV-2 virus exists in the genitourinary system of the complex squamous epithelium, sexual intercourse caused epidermal damage, the virus can be invaded genital scarring caused by HSV-2 type, 10% by HSV-l caused.
Clinical manifestations
1, incubation period of 2-20 days, an average of 6 days.
2.First infection: for the first time, the symptoms are heavy and can be accompanied by general discomfort, such as fever, headache, etc. Most papules, small blisters or pustules appear on the vulva, followed by erosion, ulceration, self-conscious pain, lasting 1-2 weeks.
3, recurrent infection: the lesion pattern is similar to the initial infection, manifested as papules and blisters on the vulva, but the symptoms are light, healing fast, and no systemic symptoms, genital herpes is often recurrent, overwork, mental tension, systemic infection, etc. can trigger the disease, and some female patients can make the disease recurrence by menstruation.’
4, anorectal simple scars: seen in male homosexuals, the patient has pain in the anus, there is discharge, some patients can feel a sense of urgency, and sometimes small blisters can be seen in the perianal area.
Diagnostic points
1.History of unclean sexual intercourse or history of spousal sensation.
2, typical clinical manifestations.
3.If necessary, virus isolation, herpes bottom cell smear examination, indirect immunofluorescence examination of smear cells to determine the virus antigen, etc.
4.Polymerase chain reaction (PCR).
Treatment
The principle is that once the diagnosis is confirmed, timely treatment, antiviral, local cleaning, prevention of recurrent infection.
1, acyclic aconitine (Acyclo blood): oral, 5 times a day, 200mg each time, for 7 days; with obvious systemic symptoms and severe disease, intravenous drip, 5mg/kg, every 8 hours, for 5-7 days; for recurrent cases, oral 200mg, 5 times a day, for 5 days, or 300mg, twice a day, for 5 days.
2. Local cleaning, washing with 1:5000 potassium permanganate solution, etc., topical application of herpes net solution, phthalbutamide application, etc.
3. For cases with frequent recurrence, immune booster can be used.
Prevention
1.Apply condoms, especially for recurrent scarlet rash, often as carriers of the virus, condoms should be used during sexual intercourse.
2.If the fetus is infected with scarlet rash in the genital area within 3 months of pregnancy, abortion should be performed, and if the fetus is infected with scarlet rash at the end of pregnancy, caesarean section should be performed because of the possibility of infection to the fetus during delivery.