Hemodialysis is hemodialysis, during hemodialysis, there is generally no feeling, except for patients with fistula, when the fistula slightly painful feeling, and the needle in the wrong direction will be a little uncomfortable. There is no feeling during regular dialysis, except for complications, such as dialysis hypotension, dialysis with arrhythmia, etc. In case of dialysis hypotension, there may be discomfort such as dizziness, panic, sweating, nausea, vomiting and twitching of legs. When dialysis is accompanied by arrhythmia, there may be paroxysmal supraventricular tachycardia or rapid atrial fibrillation, and there will be a feeling of panic, but at other times there is usually no feeling.