Cold and hot may be hot and cold, generally considered to be malaria, typhoid fever, infectious diseases and menopausal syndrome caused. 1. Malaria: It may be caused by external wind-cold and summer dampness, the more common clinical symptoms are cold and hot, and may cause yawning and fatigue and other symptoms. 2. Typhoid fever: generally is the typhoid bacillus induced deformity of intestinal infectious diseases, will lead to the patient to produce persistent fever, liver and spleen enlargement, as well as the expression of indifference and other symptoms. 3. Infectious diseases: such as upper respiratory tract infections, digestive tract infections, etc., can cause pathogens to invade the human body and induce infections, leading to immune response, causing the body to be cold and hot. 4. Menopausal syndrome: may be associated with changes in the temperature of the external environment, as well as emotional fluctuations and induced by the body cold and hot. Cold and hot may also be other diseases, it is recommended that the patient to the regular hospital to receive further examination, according to the results of the treatment under the guidance of specialists, do not be negligent, so as not to delay the condition.