After infection with Salmonella typhimurium, the symptoms of pus and blood stool usually take 1~3 days to disappear, mainly symptomatic and antibacterial treatment, but do not rule out special circumstances. The disease caused by Salmonella typhimurium infection is bacterial food poisoning, which usually has a short course and is self-limiting, with the main manifestations of high fever, nausea, vomiting, diarrhea and so on. It is highly prevalent in summer and fall (June to September) and has a short incubation period. Symptoms are dominated by acute gastroenteritis, and the discharge of pus and blood stools usually lasts for 1~3 days and can be recovered, and rarely up to 1~2 weeks. It can be treated with antibiotics such as moxifloxacin, ceftriaxone, cefoperazone, etc. During the treatment, bed rest and diet should be easy to digest. If the vomiting or diarrhea is severe, metoclopramide can be taken, or injections of atropine, scopolamine and other drugs. Those with severe dehydration or even shock should be supplemented with fluids to maintain electrolyte balance. In the treatment of intestinal infectious diseases should be given quarantine, until the body temperature is normalized for 15 days and then released from quarantine. Prompt medical attention is recommended, and drugs should be used according to the doctor’s instructions.