There are many causes of scrotal discomfort, such as trauma, infection, varicocele, tumor and scrotal skin disease, etc. Further examination is needed in order to clarify the cause. 1. Trauma: before the appearance of scrotal discomfort, there is a clear history of trauma to the scrotum, such as scrotal impact, strenuous exercise, etc., which may be caused by contusion of the testicles and epididymis, testicular torsion, scrotal hematoma, etc., in addition to the discomfort, the patient may also experience severe pain in severe cases. 2. Infection: the more common are orchitis, epididymitis and folliculitis in the scrotal skin, etc. Bacterial infection is common, and some of them can be caused by viruses, tuberculosis and other disease-causing microorganisms, and there can be redness, swelling, heat and pain in the scrotum. 3. Varicocele: Mild varicocele has no discomfort, while severe varicocele can lead to swelling in the scrotum. 4. Tumor: touching the scrotum can reveal the presence of hard lumps, such as testicular cysts, testicular cancer, etc. Ultrasound examination of the scrotum can reveal the presence of masses, and if necessary, pathological examinations need to be given. 5. Scrotal skin diseases: for example, scrotal eczema, dermatitis, fungal infections, etc., the scrotum may have moist, itchy, pimples, erythema and other pathological changes. Scrotal discomfort may also be caused by other factors, it is recommended that patients go to the regular hospital, complete the auxiliary examination, in order to clarify the cause of the disease, the professional physician for the cause of the corresponding treatment.