The first and most common effect of vaginal insertion of drugs to treat vaginitis or cervicitis is the contraction of the uterus due to the stimulation of vaginal insertion of drugs, resulting in vaginal bleeding, or pain in the lower abdomen and other symptoms of pre-eclampsia. Once this happens, it is recommended to have an ultrasound examination in time to understand the development of the embryo in the uterus, and then give the treatment to stabilize the fetus according to the result. Secondly, if the effects caused by vaginal insertion of drugs in pregnancy are also directly related to the drugs inserted, the main thing is to understand whether the drug will lead to the possibility of malformation of the fetus. It is recommended to take the medication to the eugenics department of the hospital and ask the doctor whether it will cause fetal abnormalities before deciding whether to continue the pregnancy.