Cranial repair is used for cranial defects mostly due to surgical treatment, traumatic defects and congenital cranial defects. The cranial defect will not only affect the appearance aspect. In severe cases, it can also cause health risks to the patient. There are also skull repair surgeries that can be performed if the defect is severe enough to affect the appearance of the skull. Therefore, it depends on the individual case. For example, children with cranial defects will partially heal later and do not need surgery, so it is recommended to go to the hospital for an interview and consult with the doctor to decide whether repair is needed. Patients with skull defects often have a heavy burden of insecurity and can cause headaches, dizziness, fear of vibration and other syndromes. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. Therefore, cranial repair is necessary for safety reasons. It is also very important to choose the repair material. A new type of polymer PEEK material is currently available clinically, which is histocompatible, comfortable, and thicker. It is similar to human cranial bone. Especially for pediatric patients, it can better adapt to the growth and development of human autogenous cranial bone. And it will also have lower infection and rejection rates. The important point is that polyetheretherketone material is a material that can be plasticized in three dimensions, and it can be customized in three dimensions according to different patients’ conditions. It really restores the physiological structure of the skull perfectly. The surgical procedure: 1, first requires a 3D CT scan of the patient’s skull to extract accurate 3D data for 3D reconstruction and 3D printing to produce a personalized PEEK repair material that perfectly matches the structure of the bone window. 2, The scalp is incised during surgery, the layers of tissue are carefully separated to expose the bone window, and then the material is precisely affixed to the bone window and adjusted and reset. 3, well fixed with special lap screws, suture all layers of skin, and the surgery is complete. 4.After the operation, pay attention to give antibiotics to prevent infection, hemostasis and neurotrophic drug treatment; pay attention to observe the changes of the patient’s surgical cavity drainage, change medication regularly and observe the healing of the incision.