Before the “haze affects fertility” comment became a current social issue, there were numerous studies warning of the relationship between increasing global environmental pollution and the rapidly declining sperm count and quality in humans. “Suspended air pollutants” can affect the normal secretion of male hormones, leading to sexual failure. Toxic substances can also cause impaired spermatogenesis and normal development. Over the past 50 years, the number of sperm per milliliter of semen in men has dropped from 200 million to 20 million, and even the normal range of semen tests has had to be lowered. At the same time, the rate of abnormalities and malformations of human sperm has risen markedly, so that the proportion of male infertility is also increasing year by year. Similarly, various environmental pollutants can cause endocrine disruption in women, leading to menstrual disorders, infertility, or hypogonadism. Couples suffering from infertility have been pinning their fertility hopes on medically assisted reproduction techniques. However, artificial insemination is not suitable for every infertile couple. It is mainly used for infertility caused by male factors, such as mild oligozoospermia, abnormal semen liquefaction, impotence, severe hypospadias, retrograde ejaculation and other sexual dysfunctions. Wendy Deng, the ex-wife of American media mogul Murdoch, precisely used Murdoch’s frozen sperm in advance for artificial insemination and successfully gave birth to two daughters. Some female factors such as vaginal spasm sexual intercourse difficulties, ovulation disorders, cervical factors leading to infertility, mild to moderate endometriosis, unexplained infertility, etc. can also be assisted by artificial insemination. For those whose husbands suffer from azoospermia or have serious genetic diseases that make them unfit for childbearing, they can apply for artificial insemination using donated sperm to assist conception. Many infertile couples confuse artificial insemination for in vitro fertilization (IVF), which is actually two different techniques for assisted conception. In vitro fertilization (IVF) involves retrieving eggs by puncture, combining them with sperm outside the body, culturing them to form a fertilized egg and then transplanting them into the woman’s uterus. Artificial insemination (IUI), on the other hand, involves selecting the time of ovulation to introduce optimized male sperm into the woman’s reproductive tract. Compared to IVF, artificial insemination has a lower conception rate, with a success rate of 10-15%, but it is simpler, less costly and easier to perform. The prerequisite for the implementation of artificial insemination is that at least one side of the female’s fallopian tubes are open, and then through vaginal ultrasound to monitor follicular development, close to ovulation or within 24 hours after ovulation, the male party to use the method of masturbation to collect semen, the reproduction laboratory through the washing of sperm, removing inflammatory cells in the seminal plasma to affect the fertilization of the sperm plasma, anti-sperm antibodies and other harmful substances, the sperm will be resuspended in the culture fluid with better vitality, and finally concentrated to 0.5 ml of sperm suspension, with a 0.5 ml of sperm suspension. The sperm is resuspended in a culture medium and finally concentrated into 0.5 ml of sperm suspension, which is injected into the female reproductive tract, usually directly into the uterine cavity, using a thin catheter to increase the chances of conception. The entire insemination process takes only 2-3 minutes, is painless, and allows for free movement after the procedure, and does not interfere with normal work or life. For couples who have normal sex life, if they have been trying to conceive for one year without success, it is what is known as “infertility” in medical terms. It is recommended that both husband and wife come to the fertility clinic for a checkup so that the doctor can formulate a suitable plan to help them conceive so that a healthy baby can come as soon as possible.