Oral Naproxen is not recommended after drinking alcohol. Naproxen is mainly used for the treatment of rheumatic and rheumatoid arthritis, osteoarthritis, osteoarthritis, mandatory spondylitis, gout and other diseases, as a non-steroidal drug. Taking naproxen after drinking alcohol may affect the effect of the drug, and naproxen is mostly taken with gastrointestinal adverse reactions, taking it after drinking alcohol will aggravate the chances of gastrointestinal adverse reactions, and there may be a risk of ulcer attack. Alcohol and NSAIDs are independent risk factors for gastric mucosal damage, and drinking alcohol while taking NSAIDs will aggravate gastric mucosal damage and make it more likely to have complications such as ulcer bleeding. Therefore, taking naproxen after drinking alcohol is not recommended. When taking naproxen for treatment, it needs to be used in strict accordance with medical advice.