Ozone has a strong oxidizing power, as well as anti-inflammatory and analgesic effects. The best effect is achieved by using ozone targeted joint cavity injection treatment. The principle and steps are: 1. Intra-articular cavity puncture, repeatedly flushing the diseased joint cavity with saline several times to facilitate the elimination of inflammatory exudate and fine diseased tissue debris shed from the original diseased joint fluid and reduce inflammatory substances. 2.Eliminate the inflammation and exudation of the synovial membrane of the joint by injecting 5 – 20 ml of ozone at a concentration of 20 – 60ug/ml around the joint and in the joint cavity for 1 – 3 minutes. 3.According to the condition, it can be injected with drugs at the same time, and sodium hyaluronate, which is a physiologically necessary substance in the body, is given to the joint cavity to increase its biological function of lubrication and resistance to mechanical force. Intra-articular ozone injection therapy can eliminate joint swelling and relieve joint pain within 6 to 24 hours to treat osteoarthritis and restore joint function.