Multiple myeloma is not a terminal disease, it is a malignant proliferative disease of plasma cells within the bone marrow caused by a variety of factors such as heredity, ionizing radiation and viral infection. It can be treated by drugs, hematopoietic stem cell transplantation and other methods. 1. Clinical manifestations of multiple myeloma include bone pain, pathological fracture, anemia, hematuria, proteinuria, hypercalcemia, dizziness, ophthalmoplegia, nosebleed, gum bleed, muscle weakness, numbness of limbs and so on. 2. Asymptomatic patients with multiple myeloma do not need treatment for the time being; symptomatic patients can be treated with induction therapy, commonly used drugs include bortezomib, lenalidomide, dexamethasone, doxorubicin, cyclophosphamide, etc. Patients with no contraindication to transplantation can be treated with autologous hematopoietic stem cell transplantation or allogeneic hematopoietic stem cell transplantation after the induction therapy. In addition, patients with bone pain, hypercalcemia and renal insufficiency should also be treated with bisphosphonates, hydration, alkalinization (sodium bicarbonate tablets), diuresis (furosemide) and other targeted treatments. Warm reminder: multiple myeloma is not a terminal disease, it is a blood system disease. Once diagnosed, patients should actively cooperate with doctors for treatment.