Aspirin is generally best taken at night, after dinner to reduce the damage of aspirin to the gastric and intestinal mucosa, and can also play a role in inhibiting platelet aggregation and preventing blood clots. It is recommended that before taking aspirin orally, you should do relevant examinations, such as whether you have a history of gastrointestinal disorders, gastric ulcers, gastric bleeding, whether you have used hormones or anticoagulant drugs, all of which should be noted, otherwise the application of aspirin will aggravate the condition. Attention should also be paid to the application of aspirin in the elderly, especially for lipids, blood sugar, and blood viscosity requirements are higher. Aspirin can have a mild hypotensive effect when taken at night through regulated administration, and patients should be aware of this.