Breastfeeding with caution is recommended after Melocillin Sodium for Injection because of the possibility of sensitizing infants as well as inducing diarrhea, rashes, and Candida spp. infections. Melocillin sodium for injection is mainly used to treat sepsis, skin and soft tissue infections, purulent meningitis, peritonitis, osteomyelitis and other diseases, and it has a better antibacterial effect on Escherichia coli and Enterobacteriaceae bacteria. However, Melocillin sodium can both cross the placenta into the fetal blood circulation and be secreted with breast milk. According to the product insert, although no serious problems have been reported with the use of melocillin sodium in nursing mothers, there is a possibility of sensitizing infants and inducing diarrhea, skin rashes, and Candida spp. infections. For this reason, it should be used on a balance of probability in nursing mothers. In addition, there are certain contraindications to the use of meloxicillin sodium, which is contraindicated in people who are allergic to penicillin antibiotics and should not be used arbitrarily. Meanwhile, Melocillin sodium may induce gastrointestinal discomfort such as nausea and vomiting, as well as neutropenia, hypokalemia and other adverse reactions, which need to be observed after application.