The skull is a very important organ in the human body, a hard barrier that protects the brain and head and face, as well as an important guarantee of a smooth operating environment within the skull. Cranial defects, it is obvious that the patient’s appearance will be seriously damaged, some will be collapsed, some will be bulging, either way, will make the patient become less confident, resulting in a deep sense of inferiority; in addition, the loss of the protection of the skull, the brain tissue is easy to be damaged, prone to cause abnormalities in the cerebrospinal fluid circulation, blood supply disorders and other problems. Therefore, once a skull defect occurs, it should be treated in time. Cranial defects should be repaired as soon as possible at the right time. Generally, after the defect occurs, it takes about three months to recover from emergency treatment, and then cranial bone repair can be performed. Cranial bone repair is now a relatively routine procedure in neurosurgery, and technically there is basically little problem, but mainly lies in the quality of the repair material. At present, the titanium mesh material used in most hospitals has some unsatisfactory problems, such as rejection reaction caused by titanium mesh exposure, such as a variety of discomforts, such as postoperative patients are sensitive to heat and cold, such as affecting the postoperative CT MRI and other examinations. Currently, a new type of PEEK material has been introduced as the implant material for cranial bone repair surgery. This material has become a new favorite in the field of cranial bone repair because of its excellent performance, which is almost equivalent to that of the human skull, and can achieve very ideal cranial bone repair results. Clinically, the application of this material has also achieved great success.