In clinical practice, we often encounter patients’ families asking if they will become stupid after having inhalation anesthesia. Some children’s families also ask whether inhalation anesthesia will affect the child’s intelligence and development. It is responsible to say that there is no effect. A lot of clinical data shows that prolonged and repeated anesthesia can cause memory loss and inattention in children, but a single, short inhalation of anesthetics has basically no effect on children. Because general anesthetics cause brief, transient, reversible effects. Inhalation anesthetics have a very short duration of action and are metabolized quickly in the body, so there will be memory fade for a short time after inhalation anesthetics are used. The inhalation anesthetics will be adjusted according to the weight and age of the patient or child. Generally speaking, the use of inhalation anesthetics is safe and does not affect the child’s brain.